Cesium carbonate → (R)-5-chloro-2-fluoro-4-(9'-isopropyl-5'-methyl-6'-oxo-5',6',8',9'-tetrahydrospiro[cyclopropane-1,7'-pyrimido[5,4-b][1,4]diazepine]-2'-ylamino)-N-(1-methylpyrrolidin-3-yl)benzamide

반응식

Cl[C:2]1[N:3]=[CH:4][C:5]2[N:6]([CH3:19])[C:7](=[O:18])[C:8]3([CH2:17][CH2:16]3)[CH2:9][N:10]([CH:13]([CH3:15])[CH3:14])[C:11]=2[N:12]=1.[NH2:20][C:21]1[C:35]([Cl:36])=[CH:34][C:24]([C:25]([NH:27][C@@H:28]2[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29]2)=[O:26])=[C:23]([F:37])[CH:22]=1.CC1(C)C2C(=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=CC=2)OC2C(P(C3C=CC=CC=3)C3C=CC=CC=3)=CC=CC1=2.C(=O)([O-])[O-].[Cs+].[Cs+]>O1CCOCC1.[Pd+2].C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1>[Cl:36][C:35]1[C:21]([NH:20][C:2]2[N:3]=[CH:4][C:5]3[N:6]([CH3:19])[C:7](=[O:18])[C:8]4([CH2:17][CH2:16]4)[CH2:9][N:10]([CH:13]([CH3:15])[CH3:14])[C:11]=3[N:12]=2)=[CH:22][C:23]([F:37])=[C:24]([CH:34]=1)[C:25]([NH:27][C@@H:28]1[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29]1)=[O:26]