Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2234357생성일: 2026년 10월 26일
2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide → 4-amino-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide
https://huagongshe.com/reaction/2234357
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide | HCID 67117746 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-amino-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide | HCID 66927285 | — |
반응 단계
2-fluoro-5-methoxy-N-(1-methyl-4-piperidyl)-4-nitro-benzamide Intermediate 28; 1.3 g, 4.2 mmol) 10% Palladium on Carbon (100 mg) and Methanol (50 mL) were combined and stirred at 25° C. under Hydrogen at 1 bar pressure for 18 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07709471B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_05 |
|---|
| ORD ID | ord-9ecb695237ea4969af047f347a4c79bc |
|---|
| 출처 메모 | uspto-grants-2010_05 |
|---|
