3-(cyclopropylmethylamino)-N-methyl-propanamide → 3-[(5-bromo-2-chloro-pyrimidin-4-yl)-(cyclopropylmethyl)amino]-N-methyl-propanamide

HRID 2234398

반응식

HRID 2234398 반응식
[CH:1]1([CH2:4][NH:5][CH2:6][CH2:7][C:8]([NH:10][CH3:11])=[O:9])[CH2:3][CH2:2]1.[Br:12][C:13]1[C:14](N(C(CC)C)CCC(NC)=O)=[N:15][C:16]([Cl:19])=[N:17][CH:18]=1>>[Br:12][C:13]1[C:14]([N:5]([CH2:4][CH:1]2[CH2:2][CH2:3]2)[CH2:6][CH2:7][C:8]([NH:10][CH3:11])=[O:9])=[N:15][C:16]([Cl:19])=[N:17][CH:18]=1

참가 물질

3

반응물 2

HCID 618631993-(cyclopropylmethylamino)-N-methyl-propanamideHCID 866175713-[(5-bromo-2-chloro-pyrimidin-4-yl)-butan-2-yl-amino]-N-methyl-propanamide

생성물 1

HCID 866175743-[(5-bromo-2-chloro-pyrimidin-4-yl)-(cyclopropylmethyl)amino]-N-methyl-propanamide

실험 절차

Using 3-(cyclopropylmethylamino)-N-methyl-propanamide—Intermediate 95 and analogous conditions to Intermediate 88 the title compound was obtained as a white solid (431 mg)

출처 및 근거

ORD 기록
ord-8cfeb1351cc14cd8978467eb849c6d62
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07709471B2

연결된 노트

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