Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium borohydride → (2,6-Dichloro-3-methoxyphenyl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 2,6-Dichloro-3-methoxybenzaldehyde | HCID 14927173 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (2,6-Dichloro-3-methoxyphenyl)methanol | HCID 21980844 | 93.3% |
반응 단계
Dissolve 2,6-dichloro-3-methoxy-benzaldehyde (10 g, 48.8 mmol) in ethanol (330 ml) add sodiumborohydride (1.8 g, 48.8 mmol) and stir at room temperature over night. Partition reaction mixture between water and ethyl acetate separate layers wash organic with brine, dry over sodium sulfate, filter and concentrate to yield 9.43 g (93%) of (2,6-Dichloro-3-methoxy-phenyl)-methanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07713979B2 |
| 출처 데이터셋 | uspto-grants-2010_05 |
| ORD ID | ord-5126c216c3c74222ac698c14d245ede7 |
| 출처 메모 | uspto-grants-2010_05 |