Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Neoviridogrisein IV → N-Methyl-N-phenyl-glycine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Neoviridogrisein IV | HCID 196972 | — |
| 반응물 | 3-Hydroxy-N-(24-Hydroxy-7,11,13,17,20-Pentamethyl-16-(3-Methylbutan-2-Yl)-3-(2-Methylpropyl)-2,5,9,12,15,18,21-Heptaoxo-10-Phenyl-8-Oxa-1,4,11,14,17,20-Hexazabicyclo(20.3.0)Pentacosan-6-Yl)Pyridine-2-Carboxamide | HCID 417256 | — |
| 반응물 | (1S,9R,11S,12Z,14Z,19Z,22R)-9,11-Dihydroxy-22-methyl-6,23-dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione | HCID 6441064 | — |
| 생성물 | N-Methyl-N-phenyl-glycine | HCID 420843 | — |
반응 단계
In addition the identity of neoviridogrisein IV with viridogrisein was further confirmed by IR, UV, NMR and mass spectrometry, thin layer chromatography, hydrolysate analysis and antimicrobial spectrometry. On the other hand, the griseoviridin preparation obtained in Example 5 was crystallized in warm methanol to yield needle crystals. Then a part of the needle crystals were compared and identified with an authentic preparation of griseoviridin by IR, UV, NMR and mass spectrometry, thin layer chromatography, elementary analysis and other physico-chemical properties.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04355112 |
| 출처 데이터셋 | uspto-grants-1982_10 |
| ORD ID | ord-517422c010fe47a2a29a2371a659c8a6 |
| 출처 메모 | uspto-grants-1982_10 |