Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Diflunisal
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylate | HCID 491921 | — |
| 생성물 | Diflunisal | HCID 3059 | — |
반응 단계
The product of Step A above is suspended in 8.0 ml. of aqueous sodium hydroxide (5%) and refluxed for 30 minutes. The mixture is acidified with aqueous hydrochloric acid and extracted three times with 15.0 ml. of toluene. The combined toluene extracts are concentrated to afford 2.3 mmole of 5-(2,4-difluorophenyl)salicylic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04355174 |
| 출처 데이터셋 | uspto-grants-1982_10 |
| ORD ID | ord-1345b11bb9a5477eab8447663fa01bdd |
| 출처 메모 | uspto-grants-1982_10 |