2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → HCID 59301338, 화합물

HRID 2236239노트

반응식

HRID 2236239 반응식
[C:1]1([C:7]2[O:8][C:9]([C:15]([F:18])([F:17])[F:16])=[C:10]([C:12]([OH:14])=O)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:19]([N:21]([CH3:29])[C:22]1[CH:27]=[CH:26][C:25]([NH2:28])=[CH:24][N:23]=1)[CH3:20]>>[CH2:19]([N:21]([CH3:29])[C:22]1[N:23]=[CH:24][C:25]([NH:28][C:12]([C:10]2[N:11]=[C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[O:8][C:9]=2[C:15]([F:18])([F:17])[F:16])=[O:14])=[CH:26][CH:27]=1)[CH3:20]

참가 물질

3

반응물 2

HCID 27764382-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 43263136HCID 43263136, 화합물

생성물 1

HCID 59301338HCID 59301338, 화합물

실험 절차

With a procedure similar to example 16 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid [6-(ethyl-methyl-amino)-pyridin-3-yl]-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and N2-ethyl-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C19H17F3N4O2 (m/e) 390, obsd 391 (M+H).

출처 및 근거

ORD 기록
ord-0af77ad7f184450cb4d9abead7b7bcc6
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07714126B2

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