HCID 43263136, 화합물 → 2-Phenyl-4-propyl-oxazole-5-carboxylic acid [6-(ethyl-methyl-amino)-pyridin-3-yl]amide

HRID 2236300노트

반응식

HRID 2236300 반응식
O=C1CCC(=O)N1O[C:9]([C:11]1[O:15][C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[N:13][C:12]=1[CH2:22][CH2:23][CH3:24])=[O:10].[CH2:25]([N:27]([CH3:35])[C:28]1[CH:33]=[CH:32][C:31]([NH2:34])=[CH:30][N:29]=1)[CH3:26]>>[CH2:25]([N:27]([CH3:35])[C:28]1[N:29]=[CH:30][C:31]([NH:34][C:9]([C:11]2[O:15][C:14]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)=[N:13][C:12]=2[CH2:22][CH2:23][CH3:24])=[O:10])=[CH:32][CH:33]=1)[CH3:26]

참가 물질

3

반응물 2

HCID 43263136HCID 43263136, 화합물HCID 593012952-Phenyl-4-propyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

생성물 1

HCID 593013042-Phenyl-4-propyl-oxazole-5-carboxylic acid [6-(ethyl-methyl-amino)-pyridin-3-yl]amide

실험 절차

With a procedure similar to example 50 above, 2-phenyl-4-propyl-oxazole-5-carboxylic acid [6-(ethyl-methyl-amino)-pyridin-3-yl]-amide was prepared from 2-phenyl-4-propyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester and N2-ethyl-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C21H24N4O2 (m/e) 364, obsd 365 (M+H).

출처 및 근거

ORD 기록
ord-6c0dd0fd08d24f2594df4e26c2fcfd27
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07714126B2

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