4-Chloromethyl-2-methoxy-biphenyl → 4-Chloromethyl-4'-fluoro-2-methoxy-biphenyl

반응식

[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:5]([O:15][CH3:16])[CH:4]=1.[F:17]C1C=CC(C2C=CC(CO)=CC=2OC)=CC=1>>[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([F:17])=[CH:11][CH:10]=2)=[C:5]([O:15][CH3:16])[CH:4]=1

참가 물질

반응물 2

HCID 593001244-Chloromethyl-2-methoxy-biphenyl

HCID 59300176(4'-Fluoro-2-methoxy-biphenyl-4-yl)-methanol

생성물 1

HCID 593001834-Chloromethyl-4'-fluoro-2-methoxy-biphenyl

실험 절차

Following the same procedure for the preparation of 4-Chloromethyl-2-methoxy-biphenyl, the title compound is prepared from (4′-Fluoro-2-methoxy-biphenyl-4-yl)-methanol (crude material from the previous step). The crude material is used directly in the next step.

출처 및 근거

ORD 기록: ord-aaa9e36d84f14fa7b7d01fd351cf8d48
출처 데이터셋: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07713994B2

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