Tert-butyl 2-(4-aminophenyl)pyrrolidine-1-carboxylate → 4-(1-Allyl-pyrrolidin-2-yl)-phenylamine

HRID 2236514노트

반응식

HRID 2236514 반응식
C(O[C:6]([N:8]1[CH2:12][CH2:11][CH2:10][CH:9]1[C:13]1[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=1)=O)(C)(C)C.[CH2:20](N1CCCC1C1C=CC(Br)=CC=1)[CH:21]=C>>[CH2:6]([N:8]1[CH2:12][CH2:11][CH2:10][CH:9]1[C:13]1[CH:14]=[CH:15][C:16]([NH2:19])=[CH:17][CH:18]=1)[CH:20]=[CH2:21]

참가 물질

3

반응물 2

HCID 44607625Tert-butyl 2-(4-aminophenyl)pyrrolidine-1-carboxylateHCID 513585141-Allyl-2-(4-bromo-phenyl)-pyrrolidine

생성물 1

HCID 593002364-(1-Allyl-pyrrolidin-2-yl)-phenylamine수율 87%

실험 절차

Using the same procedure described for the preparation of 2-(4-Amino-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester, the title compound is prepared from 1-Allyl-2-(4-bromo-phenyl)-pyrrolidine (470 mg, 1.77 mmol) in 87% yield.

출처 및 근거

ORD 기록
ord-eb038161912042d88aa2d57b7d60aaf5
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07713994B2

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