4-(Piperidin-1-ylmethyl)aniline → HCID 178518386, 화합물
반응식
ClC1C=C(N/C=C2\C(=O)NC(=O)C3C\2=CC=CC=3)C=CC=1SC1N(C)C=CN=1.CO/[CH:31]=[C:32]1/[C:33](=[O:46])[NH:34][C:35](=[O:45])[C:36]2[C:41]/1=[CH:40][C:39]([N+:42]([O-:44])=[O:43])=[CH:38][CH:37]=2.[N:47]1([CH2:53][C:54]2[CH:59]=[CH:58][C:57]([NH2:60])=[CH:56][CH:55]=2)[CH2:52][CH2:51][CH2:50][CH2:49][CH2:48]1>>[CH2:50]1[CH2:51][CH2:52][N:47]([CH2:53][C:54]2[CH:55]=[CH:56][C:57]([NH:60]/[CH:31]=[C:32]3/[C:41]4[CH:40]=[C:39]([N+:42]([O-:44])=[O:43])[CH:38]=[CH:37][C:36]=4[C:35]([NH:34][C:33]/3=[O:46])=[O:45])=[CH:58][CH:59]=2)[CH2:48][CH2:49]1참가 물질
4
실험 절차
Using the procedure described for (4Z)-4-[({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}amino)methylene]isoquinoline-1,3(2H,4H)-dione, 115 mg (0.46 mmol) of (4E)-4-(methoxy)methylene-6-nitroisoquinoline-1,3(2H,4H)-dione is reacted with 93 mg (0.49 mmol) of 4-piperidin-1-ylmethyl-phenylamine to give 137 mg (73%) of brown solid, mp 225-235 (dec); MS (ES−) m/z 405.2 (M−H)−1.