3-Aminomethyl-4-furan-2-yl-phenol → HCID 178518374, 화합물
반응식
[OH:1][C:2]1[CH:7]=[C:6]([CH2:8][NH:9][CH:10]=[C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[C:18]([I:21])[CH:19]=3)[C:14](=[O:22])[NH:13][C:12]2=[O:23])[CH:5]=[CH:4][C:3]=1C1C=CC=CC=1.IC1C=C2C(=CC=1)C(=O)N[C:35](=O)[C:34]2=[CH:43][O:44][CH3:45].NCC1C=C(O)C=CC=1C1OC=CC=1>>[O:44]1[CH:43]=[CH:34][CH:35]=[C:45]1[C:5]1[CH:4]=[CH:3][C:2]([OH:1])=[CH:7][C:6]=1[CH2:8][NH:9][CH:10]=[C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[C:18]([I:21])[CH:19]=2)[C:14](=[O:22])[NH:13][C:12]1=[O:23]참가 물질
4
실험 절차
Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione, the title compound is prepared from 6-iodo-4-methoxymethylene-4H-isoquinoline-1,3-dione (100 mg, 0.30 mmol) and 3-Aminomethyl-4-furan-2-yl-phenol (crude material from the previous reaction in 56% yield: MS (ESI): 485.1 (M−1)−1.