Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → alpha-(2-Methylpropylidene)pyridine-2-acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Isobutyraldehyde | HCID 6561 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | Pyridine-2-acetonitrile | HCID 75959 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | alpha-(2-Methylpropylidene)pyridine-2-acetonitrile | HCID 90767 | — |
반응 단계
In a flask equipped with a water separator are placed 7 g of 2-pyridyl acetonitrile, 12.8 g of isobutyraldehyde, 0.9 ml of acetic acid, 0.18 ml of piperidine and 250 ml of dry benzene. The mixture is heated under reflux for 3 hours. After cooling, the reaction mixture is washed with water, the organic phase is dried over sodium sulfate then the solvent is evaporated to dryness.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04356177 |
| 출처 데이터셋 | uspto-grants-1982_10 |
| ORD ID | ord-8c24038a3fed4ea884fea50cdda5a581 |
| 출처 메모 | uspto-grants-1982_10 |