Imipramine → CID 16052002

HRID 2237400노트

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HRID 2237400 반응식
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][N:7]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH2:15][CH2:14][C:13]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]1=2)[CH3:3].[CH:22]1[CH:23]=[CH:24][C:25]2[C:26](=[CH:28][C:29]([C:48]([OH:50])=[O:49])=[C:30]([OH:47])[C:31]=2[CH2:32][C:33]2[C:42]([OH:43])=[C:41]([C:44]([OH:46])=[O:45])[CH:40]=[C:39]3[C:34]=2[CH:35]=[CH:36][CH:37]=[CH:38]3)[CH:27]=1.C1C=C2C=C(C(O)=O)C(O)=C(CC3C4C(=CC=CC=4)C=C(C(O)=O)C=3O)C2=CC=1.[Na+]>O>[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][N:7]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=2[CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]1=2)[CH3:3].[CH:22]1[CH:23]=[CH:24][C:25]2[C:26](=[CH:28][C:29]([C:48]([OH:50])=[O:49])=[C:30]([OH:47])[C:31]=2[CH2:32][C:33]2[C:42]([OH:43])=[C:41]([C:44]([OH:46])=[O:45])[CH:40]=[C:39]3[C:34]=2[CH:35]=[CH:36][CH:37]=[CH:38]3)[CH:27]=1

참가 물질

5

반응물 3

HCID 3696Imipramine3회HCID 8546Pamoic Acid2회HCID 10179807Disodium methylenebis(2-hydroxy-3-naphthoate)

생성물 1

HCID 16052002CID 16052002

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The pamoate salt of Imipramine can be prepared by treatment of Imipramine with pamoic salt or pamoic acid in a solvent or solvent mix. Imipramine pamoate was prepared by adding a solution of imipramine in an appropriate solvent, e.g. acidic water, to a solution of disodium pamoate, pamoic acid or other pamoate salt and stirred resulting in precipitation of the salt.

후처리

  1. additionmix
  2. customresulting in precipitation of the salt

출처 및 근거

ORD 기록
ord-c01f26a100e645d6b8259bc50ec03d4a
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07718649B1

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