참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-Ethoxyaniline | HCID 9076 | — |
| 반응물 | 3,8-Dibromo-6-chloroimidazo[1,2-b]pyridazine | HCID 44630723 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-bromo-6-chloro-N-(4-ethoxyphenyl)imidazo[1,2-b]pyridazin-8-amine | HCID 86611739 | — |
반응 단계
p-Phenetidine (0.38 ml, 2.9 mmol) and triethylamine (0.8 ml, 5.8 mmol) were added to a mixture of 3,8-dibromo-6-chloroimidazo[1,2-b]pyridazine (0.83 g, 2.67 mmol) from 1a in EtOH (10 mL). The mixture was heated to 80° C. and stirred for 16 hrs. The solution was then concentrated in vacuo to give crude 3-bromo-6-chloro-N-(4-ethoxyphenyl)imidazo[1,2-b]pyridazin-8-amine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07723336B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_05 |
|---|
| ORD ID | ord-22aefa9687de43a08b620f0d46b1c95b |
|---|
| 출처 메모 | uspto-grants-2010_05 |
|---|
