Dichloromethane → HCID 68428933, 화합물

HRID 2240287노트

반응식

HRID 2240287 반응식
ClCCl.[CH3:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][NH2:13])=[CH:8][CH:7]=1.C(N(CC)CC)C.[C:21](Cl)(=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23]>O>[CH3:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][NH:13][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])=[CH:8][CH:7]=1

참가 물질

6

반응물 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 77023(4-Methoxyphenyl)hydrazine

생성물 1

HCID 68428933HCID 68428933, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a mixture of 50 ml of dichloromethane and 2.76 g of free 4-methoxyphenyl-hydrazine there are added first 2.2 g of triethylamine and then, dropwise, at a temperature of from 0° to 5°, 2.65 g of pivaloyl chloride. The reaction mixture is stirred for 12 hours at room temperature and then discharged into water. The aqueous mixture is extracted with dichloromethane, the extract is concentrated and the residue is recrystallised from toluene/pentane, yielding N-(4-methoxyphenyl)-N′-pivaloyl-hydrazine which melts at from 126° to 127°.

후처리

  1. extractionThe aqueous mixture is extracted with dichloromethane
  2. concentrationthe extract is concentrated
  3. customthe residue is recrystallised from toluene/pentane

출처 및 근거

ORD 기록
ord-2fabd1ebcf9a44c6b47c6be027082d0f
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07723362B2

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