3-(5-Methoxy-1H-indol-3-yl)propanoic acid → HCID 18449999, 화합물

HRID 2240537노트

반응식

HRID 2240537 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH:7]=[C:6]2[CH2:12][CH2:13][C:14]([OH:16])=[O:15].[S:17]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18]1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([S:22]([C:19]1[CH:20]=[CH:21][S:17][CH:18]=1)(=[O:24])=[O:23])[CH:7]=[C:6]2[CH2:12][CH2:13][C:14]([OH:16])=[O:15]

참가 물질

3

반응물 2

HCID 1811373-(5-Methoxy-1H-indol-3-yl)propanoic acidHCID 2776378Thiophene-3-sulfonyl Chloride

생성물 1

HCID 18449999HCID 18449999, 화합물

실험 절차

3-[5-Methoxy-1-(thiophene-3-sulfonyl)-1H-indol-3-yl]-propionic acid 99 was prepared from 3-(5-methoxy-1H-indol-3-yl)-propionic acid 96 and 3-thienyl-sulfonyl chloride using the same protocol as described in step 8, Example 4. (M−1, 364.4)

출처 및 근거

ORD 기록
ord-25963e9e355a41bb853d757c926a8477
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07723374B2

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