HCID 66916056, 화합물 → HCID 66915943, 화합물
반응식
[CH3:1][N:2]([CH3:16])[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-])=O)[C:4]=1[S:12]([NH2:15])(=[O:14])=[O:13]>[Pd].CO>[NH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([N:2]([CH3:16])[CH3:1])[C:4]=1[S:12]([NH2:15])(=[O:13])=[O:14]참가 물질
4
실험 절차
A mixture of 2-dimethylamino-6-nitro-benzenesulfonamide (753 mg, 3.07 mmol), Pd (10%) on charcoal (100 mg) and methanol (25 ml) is hydrogenated at 25° C. for 2 h. Pd is removed by filtration, the solvent evaporated and the residue crystallized from TBME/cyclohexane to give 2-amino-6-dimethylamino-benzenesulfonamide as a colorless solid.
후처리
- customPd is removed by filtration
- customthe solvent evaporated
- customthe residue crystallized from TBME/cyclohexane
출처 및 근거
- ORD 기록
- ord-70de39517bb84abd9bd3866ddf0804cc
- 출처 데이터셋
- uspto-grants-2010_03
- 특허 번호
- US07671063B2
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