3-({5-[5-(4-Isobutyl-phenyl)-[1,2,4]oxadiazol-3-yl]-pyrazin-2-ylmethyl}-amino)-cis-cyclobutanecarboxylic acid → HCID 178440767, 화합물

HRID 2242250노트

반응식

HRID 2242250 반응식
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[O:15][N:14]=[C:13]([C:16]3[CH:17]=[CH:18][C:19](C=O)=[N:20][CH:21]=3)[N:12]=2)=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].C(C1C=CC(C2ON=C(C3N=CC([CH2:45][NH:46][CH:47]4[CH2:50][CH:49]([C:51]([OH:53])=[O:52])[CH2:48]4)=NC=3)N=2)=CC=1)C(C)C>>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11]2[O:15][N:14]=[C:13]([C:16]3[CH:17]=[CH:18][C:19]([CH2:45][NH:46][C@@H:47]4[CH2:50][C@H:49]([C:51]([OH:53])=[O:52])[CH2:48]4)=[N:20][CH:21]=3)[N:12]=2)=[CH:9][CH:10]=1)[CH:2]([CH3:4])[CH3:3]

참가 물질

3

반응물 2

HCID 177573723-({5-[5-(4-Isobutyl-phenyl)-[1,2,4]oxadiazol-3-yl]-pyrazin-2-ylmethyl}-amino)-cis-cyclobutanecarboxylic acidHCID 592042725-[5-(4-Isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyridine-2-carbaldehyde

생성물 1

HCID 178440767HCID 178440767, 화합물

실험 절차

The title compound was prepared from 5-[5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyridine-2-carbaldehyde by procedures analogous to those described in Examples (1A-1B) for the preparation of 3-({5-[5-(4-isobutyl-phenyl)-[1,2,4]oxadiazol-3-yl]-pyrazin-2-ylmethyl}-amino)-cyclobutanecarboxylic acid.

출처 및 근거

ORD 기록
ord-823a90cb9090482abc10ad87d58e40b6
출처 데이터셋
uspto-grants-2010_03
특허 번호
US07671043B2

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