HCID 59204300, 화합물 → HCID 178426496, 화합물
반응식
CO[C:3](=O)[C:4]1C=CC(C2N=C(C3C=CC(CC(C)C)=CC=3)ON=2)=C(C)[CH:5]=1.[CH2:27]([C:31]1[CH:36]=[CH:35][C:34]([C:37]2[O:41][N:40]=[C:39]([C:42]3N=CC(C=O)=N[CH:47]=3)[N:38]=2)=[CH:33][CH:32]=1)[CH:28]([CH3:30])[CH3:29].C(C1C=CC(C2ON=C(C3N=[CH:67][C:68]([CH2:71][NH:72][C@@H:73]4[CH2:76][C@H:75]([C:77]([OH:79])=[O:78])[CH2:74]4)=NC=3)N=2)=CC=1)C(C)C>>[CH2:27]([C:31]1[CH:32]=[CH:33][C:34]([C:37]2[O:41][N:40]=[C:39]([C:42]3[CH:47]=[CH:67][C:68]([CH2:71][NH:72][C@@H:73]4[CH2:74][C@H:75]([C:77]([OH:79])=[O:78])[CH2:76]4)=[CH:3][C:4]=3[CH3:5])[N:38]=2)=[CH:35][CH:36]=1)[CH:28]([CH3:29])[CH3:30]참가 물질
4
실험 절차
The title compound was prepared from 4-[5-(4-isobutyl-phenyl)-[1,2,4]oxadiazol-3-yl]-3-methyl-benzoic acid methyl ester by procedures analogous to those described in Preparations (6F-6G) and Examples (1A-1B) for the preparation of 5-[5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyrazine-2-carbaldehyde and 3-({5-[5-(4-isobutyl-phenyl)-[1,2,4]oxadiazol-3-yl]-pyrazin-2-ylmethyl}-amino)-cis-cyclobutanecarboxylic acid, respectively.