Sodium Iodide → Benzene, (8-iodooctyl)-

HRID 22430노트

반응식

HRID 22430 반응식
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[I-:16].[Na+]>CC(C)=O>[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][I:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 5238Sodium IodideHCID 2901511-Chloro-8-phenyloctane

생성물 1

HCID 10947018Benzene, (8-iodooctyl)-

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A mixture of 8-phenyloctyl chloride (4.4 g), sodium iodide (5.34 g) and acetone (20 ml) was heated under reflux for 20 hours. Evaporated, water (20 ml) added and extracted with diethyl ether (20 ml). The extracts were dried, filtered and evaporated to a pale yellow liquid (5.5 g). Distilled to give 8-phenyloctyl iodide, b.p. 200° C. (air bath temperature) at 0.1 mBar.

후처리

  1. temperaturewas heated
  2. temperatureunder reflux for 20 hours
  3. customEvaporated
  4. additionwater (20 ml) added
  5. extractionextracted with diethyl ether (20 ml)
  6. customThe extracts were dried
  7. filtrationfiltered
  8. customevaporated to a pale yellow liquid (5.5 g)
  9. distillationDistilled

출처 및 근거

ORD 기록
ord-fcbfdb0afc3740d1a45acd0665c464c3
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05428065

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