(2-Fluoro-5-phenoxyphenyl)methanol → 2-Fluoro-5-phenoxybenzyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate
반응식
[F:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([OH:16])=[O:15].[F:20][C:21]1[CH:28]=[CH:27][C:26]([O:29][C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)=[CH:25][C:22]=1[CH2:23]O>>[F:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([O:16][CH2:23][C:22]1[CH:25]=[C:26]([O:29][C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH:27]=[CH:28][C:21]=1[F:20])=[O:15]참가 물질
3
실험 절차
The acid chloride of 2(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with 2-fluoro-5-phenoxybenzyl alcohol using the procedure of Example 1 to give 2-fluoro-5-phenoxybenzyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate.
출처 및 근거
- ORD 기록
- ord-021a99e69e654f0b968d73d958d507db
- 출처 데이터셋
- uspto-grants-1980_11