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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2243387생성일: 2026년 10월 26일

p-(Trifluoromethoxy)phenyl isocyanate → 1-(6-Bromo-2-(2-(2-ethoxypropan-2-yl)phenoxy)pyridin-3-yl)-3-(4-(trifluoromethoxy)phenyl)urea

https://huagongshe.com/reaction/2243387

반응식

참여 물질

역할이름HCID투입량
반응물p-(Trifluoromethoxy)phenyl isocyanateHCID 92298—
반응물6-Bromo-2-(2-(2-ethoxypropan-2-yl)phenoxy)pyridin-3-amineHCID 86601896—
생성물1-(6-Bromo-2-(2-(2-ethoxypropan-2-yl)phenoxy)pyridin-3-yl)-3-(4-(trifluoromethoxy)phenyl)ureaHCID 86601895—

반응 단계

Example 582 was prepared from 6-bromo-2-(2-(2-ethoxypropan-2-yl)phenoxy)pyridin-3-amine and p-trifluoromethoxyphenyl isocyanate according to the procedure described for Example 2. (M-EtO)=508, 510. 1H NMR (400 MHz, DMSO-d6) ppm 0.82 (t, J=7.0 Hz, 3H), 1.53 (s, 6H), 3.21 (q, J=7.0 Hz, 2H), 7.21 (dd, J=8.1, 1.3 Hz, 1H), 7.30 (m, 6H), 7.56 (m, 4H), 8.49 (d, J=8.4 Hz, 1H), 8.73 (s, 1H), 9.61 (s, 1H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07674828B2
출처 데이터셋uspto-grants-2010_03
ORD IDord-cedb7b8b92054ad49590b3459c7cb847
출처 메모uspto-grants-2010_03