Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Dimethoxybenzoic Acid → 3-Bromo-2,6-dimethoxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Dimethoxybenzoic Acid | HCID 15109 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 3-Bromo-2,6-dimethoxybenzoic acid | HCID 2774744 | — |
반응 단계
A solution of 15 ml of bromine (0.3 mol) in 50 ml of chloroform is added dropwise while stirring and cooling in ice to 54.9 g (0.3 mol) of 2,6-dimethoxybenzoic acid in 150 ml of dioxan. The solution is left at room temperature overnight. The solvent is evaporated and the residue recrystallized from aqueous ethanol. Yield: 59.3 g, m.p. 144°-45° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04232037 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-4a69d9981df04110bfcdd27b9a858423 |
| 출처 메모 | uspto-grants-1980_11 |