Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuryl chloride → 3-Bromo-5-chloro-2,6-dimethoxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 반응물 | 3-Bromo-2,6-dimethoxybenzoic acid | HCID 2774744 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-Bromo-5-chloro-2,6-dimethoxybenzoic acid | HCID 2800463 | — |
반응 단계
A solution of 40 ml (0.5 mol) of sulphuryl chloride in 100 ml of chloroform is added dropwise to a solution of 26.1 g (0.1 mol) of 3-bromo-2,6-dimethoxybenzoic acid in 150 ml of chloroform. After a night at room temperature the solution is refluxed for 45 minutes. The solvent is evaporated and the residue recrystallized from isopropyl ether - light petroleum. Yield: 23.5 g, m.p. 98.5°-100° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04232037 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-a0df755bb7b74005aa58054f65e99638 |
| 출처 메모 | uspto-grants-1980_11 |