4-Bromopyridine → HCID 11617146, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]([C:11]2[N:12]=[C:13]([CH3:17])[S:14][C:15]=2[NH2:16])=[O:10])[CH:5]=[CH:6][CH:7]=1.Br[C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]([C:11]2[N:12]=[C:13]([CH3:17])[S:14][C:15]=2[NH:16][C:19]2[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=2)=[O:10])[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 142684-Bromopyridine

HCID 11608689HCID 11608689, 화합물

생성물 1

HCID 11617146HCID 11617146, 화합물

실험 절차

The title compound was prepared by reaction of 5-amino-2-methyl-thiazole-4-carboxylic acid (3-chloro-phenyl)-amide (prepared as illustrated in example 127) with 4-bromopyridine, as follows.

출처 및 근거

ORD 기록: ord-9e2d2bd779fb436c9beb71b8be6053c6
출처 데이터셋: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07678815B2

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