Palmitic Acid → 2-Methyl-5-hexadecanoylhydroquinone

HRID 224470

반응식

HRID 224470 반응식
B(F)(F)F.[C:5]([OH:22])(=O)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[CH3:23][C:24]1[CH:30]=[C:29]([OH:31])[CH:28]=[CH:27][C:25]=1[OH:26].C([O-])(=O)C.[Na+]>O.C(Cl)Cl>[CH3:23][C:24]1[CH:30]=[C:29]([OH:31])[C:28]([C:5](=[O:22])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[CH:27][C:25]=1[OH:26]

참가 물질

7

반응물 4

HCID 985Palmitic AcidHCID 6356Boron trifluorideHCID 7253MethylhydroquinoneHCID 517045Sodium Acetate

생성물 1

HCID 147165312-Methyl-5-hexadecanoylhydroquinone

시약·촉매·용매 2

HCID 962Water용매HCID 6344Dichloromethane용매

실험 절차

Boron trifluoride was introduced with vigorous refluxing until saturation into a mixture of 27.2 g of palmitic acid, 13.7 g of 2-methylhydroquinone and 45 ml of methylene chloride. After standing overnight the mixture was refluxed for another hour and then decomposed with stirring in a solution of 25 g of sodium acetate in 220 ml of water. After 45 min the solution in methylene chloride was separated and evaporated. The residue was stirred with methanol, filtered with suction and recrystallized from n-chlorobutane.

후처리

  1. temperaturethe mixture was refluxed for another hour
  2. customAfter 45 min the solution in methylene chloride was separated
  3. customevaporated
  4. filtrationfiltered with suction
  5. customrecrystallized from n-chlorobutane

출처 및 근거

ORD 기록
ord-db9aa316efaf44f8a6f8972152474a09
출처 데이터셋
uspto-grants-1980_11
특허 번호
US04232107

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