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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2245096생성일: 2026년 10월 27일

4-Amino-2,2,6,6-tetramethylpiperidine → 4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-[(2,2,6,6-tetramethyl-4-piperidinyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-one

https://huagongshe.com/reaction/2245096

반응식

참여 물질

역할이름HCID투입량
반응물4-Amino-2,2,6,6-tetramethylpiperidineHCID 37524—
반응물4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-oneHCID 59212680—
생성물4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-[(2,2,6,6-tetramethyl-4-piperidinyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-oneHCID 44529219—

반응 단계

The title compound was prepared as described in Example 1d from 4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one and 2,2,6,6-tetramethyl-4-piperidinamine: LC-MS m/z 519 (M+H)+, 1.8 min (ret time).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07678801B2
출처 데이터셋uspto-grants-2010_03
ORD IDord-db7d6c420e7b49d59d44ebb99772f6a0
출처 메모uspto-grants-2010_03