Imidazole → HCID 12786183, 화합물
반응식
[OH:1][C:2]([CH3:11])([C:6](=[CH2:10])[CH2:7][CH2:8][CH3:9])[CH2:3][C:4]#[CH:5].N1C=CN=C1.CN(C)C=O.Cl[Si:23]([CH3:26])([CH3:25])[CH3:24]>O>[CH3:11][C:2]([O:1][Si:23]([CH3:26])([CH3:25])[CH3:24])([C:6](=[CH2:10])[CH2:7][CH2:8][CH3:9])[CH2:3][C:4]#[CH:5]참가 물질
6
실험 절차
To a solution of 25.77 g. of 4-hydroxy-4-methyl-5-methylene-1-octyne and 28.6 g. of imidazole in 50 ml. of dimethylformamide is added 22.9 g. of chlorotrimethylsilane. The mixture is stirred at room temperature for 40 minutes, poured into cold water and extracted with petroleum ether. The extract is washed with water and saturated sodium bicarbonate solution, dried over magnesium sulfate and the solvent is removed. The residue is distilled and the desired product recovered at 85°-87° C. (0.45 mm.) as a colorless liquid.
후처리
- extractionextracted with petroleum ether
- washThe extract is washed with water and saturated sodium bicarbonate solution
- dry with materialdried over magnesium sulfate
- customthe solvent is removed
- distillationThe residue is distilled
- customthe desired product recovered at 85°-87° C. (0.45 mm.) as a colorless liquid
출처 및 근거
- ORD 기록
- ord-6b20ba9a1a3041aa9d47ff2a395d4454
- 출처 데이터셋
- uspto-grants-1980_11
- 특허 번호
- US04232166
반응 노트
불러오는 중…