Zincchloride → 3-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

HRID 224571노트

반응식

HRID 224571 반응식
[Cl-:1].[Zn+2:2].[Cl-].[N:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][O:11][C:12](=[S:22])[NH:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)[CH:5]=1>COCCO>[Cl-:1].[Zn+2:2].[C:20]([C:17]1[CH:18]=[CH:19][C:14]([NH:13][C:12](=[S:22])[O:11][CH2:10][C:6]2[CH:5]=[N:4][CH:9]=[CH:8][CH:7]=2)=[CH:15][CH:16]=1)#[N:21].[Cl-:1]

참가 물질

4

반응물 2

HCID 3007855Zincchloride2회HCID 12790266O-[(Pyridin-3-yl)methyl] (4-cyanophenyl)carbamothioate

생성물 1

HCID 867365583-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

시약·촉매·용매 1

HCID 80192-Methoxyethanol용매2회

실험 절차

The zinc chloride metal salt complex of Example I is made by dissolving 3-pyridylmethyl-N-(4-cyanophenyl)thiocarbamate (2.69 g., 0.01 mole) in 75 ml. of methyl cellosolve and adding to this stirred solution; a solution of zinc chloride (0.68 g., 0.005 mole) in 10 ml. of methyl cellosolve. The resulting solution is stirred at room temperature for 18 hours. The solvent is removed in vacuo and the residue is slurried in 30 ml. of methanol and collected on a filter to give 2.5 g. melting at 174°-5° C. with decomposition.

후처리

  1. customThe solvent is removed in vacuo
  2. customof methanol and collected on
  3. filtrationa filter
  4. customto give 2.5 g

출처 및 근거

ORD 기록
ord-9f2b28fa0cdf4290bfb269046261837d
출처 데이터셋
uspto-grants-1980_11
특허 번호
US04233289

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