Aminopyrazine → HCID 11711284, 화합물
반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([S:8]([CH3:11])(=[O:10])=[O:9])[C:3]=1F.[NH2:13][C:14]1[CH:19]=[N:18][CH:17]=[CH:16][N:15]=1.Cl[C:21]1[C:30]2[C:25](=[CH:26][CH:27]=[C:28]([OH:31])[CH:29]=2)[N:24]=[CH:23][N:22]=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([S:8]([CH3:11])(=[O:10])=[O:9])[C:3]=1[O:31][C:28]1[CH:29]=[C:30]2[C:25](=[CH:26][CH:27]=1)[N:24]=[CH:23][N:22]=[C:21]2[NH:13][C:14]1[CH:19]=[N:18][CH:17]=[CH:16][N:15]=1참가 물질
4
실험 절차
The compound of Example 97 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 1,2-difluoro-3-methanesulfonylbenzene, 2-aminopyrazine and 4-chloro-6-hydroxy-quinazoline.
출처 및 근거
- ORD 기록
- ord-d052592534f240678dbe4f0103223f86
- 출처 데이터셋
- uspto-grants-2010_03