Furfurylamine → 1-n-Heptyl-3-furfuryl thiourea

HRID 224633

반응식

HRID 224633 반응식
[CH2:1]([N:8]=[C:9]=[S:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[CH2:11]([NH2:17])[C:12]1[O:16][CH:15]=[CH:14][CH:13]=1>C1C=CC=CC=1>[CH2:1]([NH:8][C:9]([NH:17][CH2:11][C:12]1[O:16][CH:15]=[CH:14][CH:13]=1)=[S:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

참가 물질

4

반응물 2

HCID 3438FurfurylamineHCID 78152Heptane, 1-isothiocyanato-

생성물 1

HCID 196508841-n-Heptyl-3-furfuryl thiourea

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

To a mixture of 3.1 grams (0.02 mole) of n-heptyl isothiocyanate and 25 milliliters of benzene was added 1.77 milliliters (0.02 mole) of furfuryl amine. The mixture was refluxed for 30 minutes on a steam bath and then evaporated under vacuum to yield 1-n-heptyl-3-furfuryl thiourea. The product was cooled and 4.1 grams (0.02 mole) of bromoethylamine hydrobromide and 25 milliliters of ethanol 2B was added. The resulting mixture was refluxed on a steam bath overnight. The solid product was removed by filtration and air dried. A yield of 5.2 grams of solid, melting point 140°-145° C., was obtained. Structure of the product was confirmed by NMR.

후처리

  1. temperatureThe mixture was refluxed for 30 minutes on a steam bath
  2. customevaporated under vacuum

출처 및 근거

ORD 기록
ord-7d6842cd54e1495b98f857e2d72c26db
출처 데이터셋
uspto-grants-1980_11
특허 번호
US04233318

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