1-Methyl-3-aminopyrazole → HCID 23160260, 화합물
반응식
F[C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[S:9]([CH3:12])(=[O:11])=[O:10].[NH2:13][C:14]1[CH:18]=[CH:17][N:16]([CH3:19])[N:15]=1.Cl[C:21]1[C:30]2[C:25](=[CH:26][CH:27]=[C:28]([OH:31])[CH:29]=2)[N:24]=[CH:23][N:22]=1>>[CH3:8][C:5]1[CH:6]=[CH:7][C:2]([O:31][C:28]2[CH:29]=[C:30]3[C:25](=[CH:26][CH:27]=2)[N:24]=[CH:23][N:22]=[C:21]3[NH:13][C:14]2[CH:18]=[CH:17][N:16]([CH3:19])[N:15]=2)=[C:3]([S:9]([CH3:12])(=[O:11])=[O:10])[CH:4]=1참가 물질
4
실험 절차
The compound of Example 147 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 1-fluoro-4-methyl-2-(methylsulfonyl)benzene, 3-amino-1-methyl-1H-pyrazole and 4-chloro-6-hydroxy-quinazoline.
출처 및 근거
- ORD 기록
- ord-98050e23714241a8bc4b1f02e1a96f16
- 출처 데이터셋
- uspto-grants-2010_03