Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalic acid dihydrate → N,N-dimethyl-3-[3-[(1-methylthio-2-nitroethenyl)amino]propoxy]benzenemethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalic acid dihydrate | HCID 61373 | — |
| 반응물 | 1,1-Bis(methylsulfanyl)-2-nitroethane | HCID 12372264 | — |
| 반응물 | 3-(3-Aminopropoxy)-N,N-dimethylbenzenemethanamine | HCID 12913950 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N,N-dimethyl-3-[3-[(1-methylthio-2-nitroethenyl)amino]propoxy]benzenemethanamine | HCID 70538402 | 64% |
반응 단계
3-(3-Aminopropoxy)-N,N-dimethylbenzenemethanamine (10 g) and 1,1-bis-(methylthio)-2-nitroethane (16 g) were heated under reflux in tetrahydrofuran for 19 hours. Oxalic acid dihydrate (1.3 g) was added and the resulting precipitate was discarded. The solvent was removed to leave the title compound as a crystalline solid (10 g) m.p. 59°-63°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04233302 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-0168655c41f94fc4b8df7f4e22af38e2 |
| 출처 메모 | uspto-grants-1980_11 |