Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxygen → ((4-Bromophenyl)ethynyl)triisopropylsilane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxygen | HCID 977 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-Bromo-4-iodobenzene | HCID 11522 | — |
| 반응물 | (Triisopropylsilyl)acetylene | HCID 2734682 | — |
| 촉매 | Copper iodide | HCID 83717 | — |
| 촉매 | HCID 178418476 | HCID 178418476 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | ((4-Bromophenyl)ethynyl)triisopropylsilane | HCID 57809595 | — |
반응 단계
11.6 mL triisopropylsilylacetylen and 14.4 mL triethylamine followed by 0.2 g copper iodide and 0.73 g bis-(triphenylphosphine)-palladium dichloride are added under argon to an oxygen-free solution of 15.0 g 4-bromo-1-iodo-benzene in 150 mL dry tetrahydrofuran. The solution is stirred for 16 h at ambient temperature and then filtered through Celite and evaporated down. The residue is purified by chromatography on silica gel (cyclohexane).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07687469B2 |
| 출처 데이터셋 | uspto-grants-2010_03 |
| ORD ID | ord-99738f654bff4a7da2cd2e1ca416f1a1 |
| 출처 메모 | uspto-grants-2010_03 |