Malonic Acid → Nitropropanedioic acid

HRID 22467

반응식

HRID 22467 반응식
[C:1]([OH:7])(=[O:6])[CH2:2][C:3]([OH:5])=[O:4].[N+:8]([O-])([O:10]C(=O)C)=[O:9]>C(O)(=O)C.C(OC(=O)C)(=O)C>[N+:8]([CH:2]([C:1]([OH:7])=[O:6])[C:3]([OH:5])=[O:4])([O-:10])=[O:9]

참가 물질

4

반응물 2

HCID 867Malonic AcidHCID 11557Acetyl nitrate

생성물 1

HCID 19816496Nitropropanedioic acid

시약·촉매·용매 1

HCID 21895370AcOH AcOAc용매

실험 절차

Nitration of malonic acid with acetyl nitrate in acetic acid/acetic anhydride was conducted to obtain nitromalonic acid. To the nitromalonic acid is added urea to obtain a condensation reaction mixture which is refluxed to form dilituric acid in situ. Various salts are separately prepared from the dilituric acid in situ using as cation sources potassium chloride, ammonia, and guanidinium chloride. The potassium diliturate salt, ammonium diliturate, guanidinium diliturate salts are each recovered and isolated by filtration.

출처 및 근거

ORD 기록
ord-1175029bb47c455caecd1dd090779881
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05428165

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