Sodium Hydroxide → 1-({5-[5-(3-Fluoro-4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl}methyl)azetidine-3-carboxylic acid

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The title compound (90 mg) was synthesized in a yield of 81% as a white crystalline solid using methyl 1-({5-[5-(3-fluoro-4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl}methyl)azetidine-3-carboxylate (0.12 g, 0.27 mmol) that was obtained in Example 23 (23g) and a 1 N aqueous solution of sodium hydroxide (0.81 mL, 0.81 mmol) by conducting the reaction similar to that mentioned in Example 3 (3e).

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