Trifluoroacetic acid → HCID 86744971, 화합물

반응식

[CH3:1][O:2][C:3](=[O:20])[CH2:4][NH:5][C:6](=[O:19])[C@H:7]([CH:16]([CH3:18])[CH3:17])[NH:8]C(OC(C)(C)C)=O.[F:21][C:22]([F:27])([F:26])[C:23]([OH:25])=[O:24]>>[F:21][C:22]([F:27])([F:26])[C:23]([OH:25])=[O:24].[CH3:1][O:2][C:3](=[O:20])[CH2:4][NH:5][C:6](=[O:19])[C@H:7]([CH:16]([CH3:17])[CH3:18])[NH2:8]

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 14235550N-[(1,1-Dimethylethoxy)carbonyl]-L-valylglycine methyl ester

생성물 1

HCID 86744971HCID 86744971, 화합물

실험 절차

t-butyloxycarbonyl-L-valyl-glycine methyl ester (1.44 g, 5 mmol) was dissolved in trifluoroacetic acid (5 ml), and the mixture was left at room temperature for 1 hour. The solution was evaporated to dryness in vacuo and the residue triturated with dry ether.

후처리

customThe solution was evaporated to dryness in vacuo
customthe residue triturated with dry ether

출처 및 근거

ORD 기록: ord-79272b99fddf470bb0548622df5394de
출처 데이터셋: uspto-grants-1991_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05037957

반응 노트

불러오는 중…