Isopropylamine → HCID 14990558, 화합물

HRID 2248309노트

반응식

HRID 2248309 반응식
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[O:9])=[CH:4][C:3]=1[N+:17]([O-:19])=[O:18].[CH3:20][CH:21]([NH2:23])[CH3:22]>O>[F:16][C:13]1[CH:14]=[CH:15][C:10]([C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:23][CH:21]([CH3:22])[CH3:20])=[C:3]([N+:17]([O-:19])=[O:18])[CH:4]=2)=[O:9])=[CH:11][CH:12]=1

참가 물질

4

반응물 2

HCID 6363IsopropylamineHCID 30155644-Chloro-4'-fluoro-3-nitrobenzophenone

생성물 1

HCID 14990558HCID 14990558, 화합물수율 97.2%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of 14 parts of (4-chloro-3-nitrophenyl) (4-fluorophenyl)-methanone in 69 parts of 2-propanamine was stirred overnight at reflux temperature. The reaction mixture was poured into water. The precipitate was filtered off and washed with water, dried, filtered and evaporated, yielding 14.7 parts (97.2%) of (4-fluorophenyl) [4-[(1-methylethyl)-amino]-3-nitrophenyl]methanone as a residue (int. 1).

후처리

  1. temperatureat reflux temperature
  2. filtrationThe precipitate was filtered off
  3. washwashed with water
  4. customdried
  5. filtrationfiltered
  6. customevaporated

출처 및 근거

ORD 기록
ord-14fbbd2795cd443084668a93f1c7d33e
출처 데이터셋
uspto-grants-1991_08
특허 번호
US05039677

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