Potassium Hydroxide → Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate

HRID 2248746노트

반응식

HRID 2248746 반응식
C(SC1SC=CC=1)(=O)C.C([S:13][C:14]1[S:18][C:17]([C:19]([O:21][CH3:22])=[O:20])=[C:16]([OH:23])[C:15]=1[CH3:24])(=O)C.[OH-].[K+]>CO>[OH:23][C:16]1[C:15]([CH3:24])=[C:14]([SH:13])[S:18][C:17]=1[C:19]([O:21][CH3:22])=[O:20]

참가 물질

5

반응물 3

HCID 14797Potassium HydroxideHCID 13133366Thiophene-2-thiol, S-acetyl-HCID 54710754Methyl 5-acetylthio-3-hydroxy-4-methylthiophene-2-carboxylate

생성물 1

HCID 54684845Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

The acetylthiothiophene of (f) above (10 mmol) was added to 30 ml of 1M potassium hydroxide in methanol. After acidification of the mixture, the mercapto thiophene was obtained, recrystallising from hexane, m.p. 86°-88° C.

출처 및 근거

ORD 기록
ord-7076ab0dd12c417cb940f3f574dd7eb8
출처 데이터셋
uspto-grants-1991_08
특허 번호
US05041461

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