Ammonia → HCID 14986276, 화합물
반응식
C([O:4][CH2:5][C:6]([NH:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[C:10]=1[C:11]#[N:12])=[O:7])(=O)C.N>CO>[OH:4][CH2:5][C:6]([NH:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([N:17]2[CH2:18][CH2:19][O:20][CH2:21][CH2:22]2)[C:10]=1[C:11]#[N:12])=[O:7]참가 물질
4
실험 절차
To a solution of 2-(acetoxyacetylamino)-6-morpholinobenzonitrile (3 g) in methanol (200 ml) is added dropwise 28% aqueous ammonia (10 ml). The mixture is stirred at room temperature for 1 hour, and thereafter, the solvent is distilled off under reduced pressure. The resulting residue is recrystallized from ethanol-water to give the title compound (1.4 g) having the following physical properties.
후처리
- distillationthe solvent is distilled off under reduced pressure
- customThe resulting residue is recrystallized from ethanol-water
출처 및 근거
- ORD 기록
- ord-92ca61aeed364cfd99a60ebe2e4b3071
- 출처 데이터셋
- uspto-grants-1991_08
- 특허 번호
- US05041462
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