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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2248789생성일: 2026년 10월 26일

2-Chlorobenzenesulfonamide → 4-[2-Chloro-5-[2-(N',N'-dimethylureido)ethyl]-1-methylindol-3-ylmethyl]-3-methoxy-N-(2-chlorophenylsulfonyl)benzamide

https://huagongshe.com/reaction/2248789

반응식

참여 물질

역할이름HCID투입량
반응물2-ChlorobenzenesulfonamideHCID 81410—
반응물4-[2-chloro-5-[2-(N',N'-dimethylureido)ethyl]-1-methylindol-3-ylmethyl]-3-methoxybenzoic acidHCID 57243738—
생성물4-[2-Chloro-5-[2-(N',N'-dimethylureido)ethyl]-1-methylindol-3-ylmethyl]-3-methoxy-N-(2-chlorophenylsulfonyl)benzamideHCID 57174681—

반응 단계

Using a similar procedure to that described in Example 2, part c, except starting from 4-[2-chloro-5-[2-(N',N'-dimethylureido)ethyl]-1-methylindol-3-ylmethyl]-3-methoxybenzoic acid, and using 2-chlorophenylsulfonamide instead of 2-methylphenylsulfonamide, the title compound was obtained (94%) as a white solid: mp 204°-206° C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05041460
출처 데이터셋uspto-grants-1991_08
ORD IDord-8b4b8fb9e324471cbdc1b600d7001bad
출처 메모uspto-grants-1991_08