5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → 2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone

HRID 224886

반응식

HRID 224886 반응식
CS[C:3]1[NH:8][C:7](=[O:9])[C:6]([CH3:10])=[CH:5][N:4]=1.[CH3:11][N:12]([CH2:14][C:15]1[O:19][C:18]([CH2:20][S:21][CH2:22][CH2:23][NH2:24])=[CH:17][CH:16]=1)[CH3:13]>N1C=CC=CC=1>[CH3:13][N:12]([CH2:14][C:15]1[O:19][C:18]([CH2:20][S:21][CH2:22][CH2:23][NH:24][C:3]2[NH:8][C:7](=[O:9])[C:6]([CH3:10])=[CH:5][N:4]=2)=[CH:17][CH:16]=1)[CH3:11]

참가 물질

4

반응물 2

HCID 1622035-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamineHCID 2405755-Methyl-2-(methylthio)pyrimidin-4(3H)-one

생성물 1

HCID 202132822-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Reaction of 2-methylthio-5-methyl-4-pyrimidone with one equivalent of 2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamine by boiling under reflux in pyridine for 48 hours gives 2-[2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone.

출처 및 근거

ORD 기록
ord-7b42068a35a74621ab68b41a0c0bab11
출처 데이터셋
uspto-grants-1980_11
특허 번호
US04234588

연결된 노트

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