Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → Indole, 3-(2-amino-2-methylpropyl)-5-bromo-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 5-Bromo-3-(2-methyl-2-nitropropyl)indole | HCID 12619661 | — |
| 촉매 | Nickel cation | HCID 934 | — |
| 생성물 | Indole, 3-(2-amino-2-methylpropyl)-5-bromo- | HCID 13259 | — |
반응 단계
5-Bromo-3-(2-methyl-2-nitropropyl)indole, 5.9 g. was reduced with Raney nichel and hydrazine hydrate according to the method of Procedure 67D. The crude product was purified by dissolving in 200 ml. of dilute hydrochloric acid, treatment with activated charcoal, filtering, and basification of the filtrate with 10% aqueous sodium hydroxide. Yield 3.8 g. of white powder, m.p. 150°-155° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04234595 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-1e15576f9e24402ea73d6f066ceafe14 |
| 출처 메모 | uspto-grants-1980_11 |