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HRID 224897생성일: 2026년 10월 26일

Hydrazine hydrate (1:1) → Indole, 3-(2-amino-2-methylpropyl)-5-bromo-

https://huagongshe.com/reaction/224897

반응식

참여 물질

역할이름HCID투입량
반응물Hydrazine hydrate (1:1)HCID 24654—
반응물5-Bromo-3-(2-methyl-2-nitropropyl)indoleHCID 12619661—
촉매Nickel cationHCID 934—
생성물Indole, 3-(2-amino-2-methylpropyl)-5-bromo-HCID 13259—

반응 단계

5-Bromo-3-(2-methyl-2-nitropropyl)indole, 5.9 g. was reduced with Raney nichel and hydrazine hydrate according to the method of Procedure 67D. The crude product was purified by dissolving in 200 ml. of dilute hydrochloric acid, treatment with activated charcoal, filtering, and basification of the filtrate with 10% aqueous sodium hydroxide. Yield 3.8 g. of white powder, m.p. 150°-155° C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04234595
출처 데이터셋uspto-grants-1980_11
ORD IDord-1e15576f9e24402ea73d6f066ceafe14
출처 메모uspto-grants-1980_11