Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Cyanide → alpha-Oxothiophen-2-acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Cyanide | HCID 8929 | — |
| 반응물 | 2-Thiopheneglyoxylic acid | HCID 77694 | — |
| 반응물 | 2-Thiophenecarbonyl chloride | HCID 78928 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | alpha-Oxothiophen-2-acetonitrile | HCID 80107 | — |
반응 단계
A process for preparing thienylglyoxylic acid which comprises reacting thiophene carboxylic acid chloride with aqueous sodium cyanide in methylene chloride solvent and in the presence of a phase transfer catalyst to form thiophene carboxylic acid cyanide and then reacting said thiophene carboxylic acid cyanide with concentrated hydrochloric acid at a temperature and for a time sufficient to form thienylglyoxylic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04234737 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-00e6599292844ef0b8b889a075c4bd4e |
| 출처 메모 | uspto-grants-1980_11 |