4-(4-Benzyloxy-3-nitro-phenyl)-morpholine → 2-amino-4-(4-morpholinyl)Phenol
반응식
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[CH:11][C:10]=1[N+:21]([O-])=O)C1C=CC=CC=1>ClCCl.C(O)C.[Pd]>[NH2:21][C:10]1[CH:11]=[C:12]([N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH:13]=[CH:14][C:9]=1[OH:8]참가 물질
5
실험 절차
Catalytic hydrogenation of 4-(4-benzyloxy-3-nitro-phenyl)-morpholine (5 g, 16 mmol) in dichloromethane (500 ml) and ethanol (500 ml) using palladium on carbon (500 mg, 10%) afforded the title compound as a grey solid (96%), MS: m/e=194(M+).
출처 및 근거
- ORD 기록
- ord-927bb99a42ed4ffbb13d87382d1699bc
- 출처 데이터셋
- uspto-grants-2008_01
- 특허 번호
- US07317007B2
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