1-(3-Aminopropyl)-2-pipecoline → HCID 69277952, 화합물

HRID 2251155노트

반응식

HRID 2251155 반응식
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][N:7]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([C:17](O)=[O:18])[CH:13]=3)[C:8]2=[O:20])=[CH:4][CH:3]=1.[CH3:23][CH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][N:25]1[CH2:30][CH2:31][CH2:32][NH2:33]>>[Cl-:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([C:17]([NH:33][CH2:32][CH2:31][CH2:30][NH+:25]4[CH2:26][CH2:27][CH2:28][CH2:29][CH:24]4[CH3:23])=[O:18])[CH:13]=3)[C:8]2=[O:20])=[CH:21][CH:22]=1

참가 물질

3

반응물 2

HCID 5202111-(3-Aminopropyl)-2-pipecolineHCID 9079397HCID 9079397, 화합물

생성물 1

HCID 69277952HCID 69277952, 화합물

실험 절차

2-(4-chloro-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-carboxylic acid (100 mg, 0.316 mmol) and 3-(2-methylpiperidin-1-yl)propan-1-amine (138 μL, 0.792 mmol) were reacted with each other. Target compound in the amount of 136 mg (87%) was obtained by following the procedure described in Example 1.

후처리

  1. customTarget compound in the amount of 136 mg (87%) was obtained

출처 및 근거

ORD 기록
ord-9e6e31508c4748829a17c87becdd9221
출처 데이터셋
uspto-grants-2008_01
특허 번호
US07319098B2

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