반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]([CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([O:25][C:26]([F:29])([F:28])[F:27])[CH:20]=2)[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=2)=[N:6][CH:7]=1.C([O:34][C:35](=[O:38])[CH2:36]Br)(C)(C)C.C(O)(C(F)(F)F)=O>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]([CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([O:25][C:26]([F:29])([F:27])[F:28])[CH:20]=2)[CH2:9][CH2:10][C:11]2[CH:12]=[CH:13][C:14]([O:17][CH2:36][C:35]([OH:38])=[O:34])=[CH:15][CH:16]=2)=[N:6][CH:7]=1참가 물질
4
실험 절차
Similarly prepared by alkylation of 4-(2-{(5-methylpyridin-2-yl)[3-(trifluoromethoxy)benzyl]amino}ethyl)phenol with tert-butyl-bromo-acetate, followed by standard TFA hydrolysis (general procedure I).
출처 및 근거
- ORD 기록
- ord-22703ab2737b4400a738bf7375d85a61
- 출처 데이터셋
- uspto-grants-2008_01
- 특허 번호
- US07319104B2
연결된 노트
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