3-Bromo-1,1,1-trifluoro-2-propanone → 2-Methyl-2-[4-(2-{[4-(trifluoromethyl)benzyl][4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]propanoic acid

HRID 2251580

반응식

HRID 2251580 반응식
[NH2:1][C:2]([N:4]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=1)[CH2:5][CH2:6][C:7]1[CH:21]=[CH:20][C:10]([O:11][C:12]([CH3:19])([CH3:18])[C:13]([O:15]CC)=[O:14])=[CH:9][CH:8]=1)=[S:3].Br[CH2:34][C:35](=O)[C:36]([F:39])([F:38])[F:37]>>[CH3:18][C:12]([O:11][C:10]1[CH:20]=[CH:21][C:7]([CH2:6][CH2:5][N:4]([CH2:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]([F:31])([F:30])[F:32])=[CH:27][CH:28]=2)[C:2]2[S:3][CH:34]=[C:35]([C:36]([F:39])([F:38])[F:37])[N:1]=2)=[CH:8][CH:9]=1)([CH3:19])[C:13]([OH:15])=[O:14]

참가 물질

3

반응물 2

HCID 790083-Bromo-1,1,1-trifluoro-2-propanoneHCID 59643246Ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate

생성물 1

HCID 596432432-Methyl-2-[4-(2-{[4-(trifluoromethyl)benzyl][4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]propanoic acid

실험 절차

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 3-bromo-1,1,1-trifluoroacetone.

출처 및 근거

ORD 기록
ord-968453f06f764f3b9749763e72f5f6dc
출처 데이터셋
uspto-grants-2008_01
특허 번호
US07319104B2

연결된 노트

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