Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorosuccinimide → 5-Chloro-2-hydroxy-3-methoxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorosuccinimide | HCID 31398 | — |
| 반응물 | 3-Methoxysalicylic acid | HCID 70140 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 5-Chloro-2-hydroxy-3-methoxybenzoic acid | HCID 676501 | — |
반응 단계
step a) 2-hydroxy-3-methoxy-benzoic acid (13) is chlorinated for example with N-chlorosuccinimide in acetic acid to yield 5-chloro-2-hydroxy-3-methoxy benzoic acid (14); step b) the methoxy group of compound (14) is reacted with hydrobromic acid in acetic acid to yield 5-chloro-2,3-dihydroxybenzoic acid (15);
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07319101B2 |
| 출처 데이터셋 | uspto-grants-2008_01 |
| ORD ID | ord-4587e8ed799b4dcfaf0764edb72fe1d0 |
| 출처 메모 | uspto-grants-2008_01 |